The 1963 SMU Mustangs football team represented Southern Methodist University (SMU) as a member of the Southwest Conference (SWC) during the 1963 NCAA University Division football season. Led by second-year head coach Hayden Fry, the Mustangs compiled an overall record of 4–7 with a conference mark of 2–5, tying for sixth place in the SWC. SMU was invited to the Sun Bowl, where they lost to Oregon.