The 1980 National League Championship Series was played between the Philadelphia Phillies and the Houston Astros from October 7 to 12. It was the 12th NLCS. Philadelphia won the series three games to two to advance to the World Series. It was the first playoff series victory in Phillies history. The Phillies went on to defeat the Kansas City Royals for their first World Series Championship. The two franchises would meet again in the 2022 World Series, nine years after the Astros switched to the American League.