The 1981 Kentucky Wildcats football team represented the University of Kentucky in the Southeastern Conference (SEC) during the 1981 NCAA Division I-A football season. In their ninth and final season under head coach Fran Curci, the Wildcats compiled a 3–8 record (2–4 against SEC opponents), finished in a tie for sixth place in the SEC, and were outscored by their opponents, 224 to 134. The team played its home games in Commonwealth Stadium in Lexington, Kentucky.