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2-MAPB is a recreational designer drug with empathogenic effects. As with other related substituted benzofuran derivatives such as 6-APB and 5-MAPB, 2-MAPB is a monoamine releaser with some selectivity for serotonin release, generally similar in pharmacological profile to MDMA but with greater activity as a directly acting agonist of 5-HT2 receptor subtypes and somewhat greater toxicity. 2-MAPB has been isolated from post-mortem toxicology screens in several drug-related fatal adverse reactions but generally only as a component of combinations of drugs, making it difficult to determine how much it contributed to the deaths. It is illegal in Japan.

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rdfs:label
  • 2-MAPB (en)
  • 2-MAPB (zh)
rdfs:comment
  • 2-MAPB is a recreational designer drug with empathogenic effects. As with other related substituted benzofuran derivatives such as 6-APB and 5-MAPB, 2-MAPB is a monoamine releaser with some selectivity for serotonin release, generally similar in pharmacological profile to MDMA but with greater activity as a directly acting agonist of 5-HT2 receptor subtypes and somewhat greater toxicity. 2-MAPB has been isolated from post-mortem toxicology screens in several drug-related fatal adverse reactions but generally only as a component of combinations of drugs, making it difficult to determine how much it contributed to the deaths. It is illegal in Japan. (en)
  • 2-MAPB是一种具有的狡詐家藥物。它和其它取代的苯并呋喃衍生物(如和)相似,是一种单胺类释放剂,可以选择释放血清素,大体上和MDMA的药理学特征相似,但作为5-HT2受体亚型,具有稍大的毒性。它在日本是非法的。 (zh)
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  • 2-MAPB (en)
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  • http://commons.wikimedia.org/wiki/Special:FilePath/2MAPB_structure.png
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  • ANJIDHKQUCZNQY-UHFFFAOYSA-N (en)
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  • W5G20WN7CL (en)
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  • 2-MAPB is a recreational designer drug with empathogenic effects. As with other related substituted benzofuran derivatives such as 6-APB and 5-MAPB, 2-MAPB is a monoamine releaser with some selectivity for serotonin release, generally similar in pharmacological profile to MDMA but with greater activity as a directly acting agonist of 5-HT2 receptor subtypes and somewhat greater toxicity. 2-MAPB has been isolated from post-mortem toxicology screens in several drug-related fatal adverse reactions but generally only as a component of combinations of drugs, making it difficult to determine how much it contributed to the deaths. It is illegal in Japan. (en)
  • 2-MAPB是一种具有的狡詐家藥物。它和其它取代的苯并呋喃衍生物(如和)相似,是一种单胺类释放剂,可以选择释放血清素,大体上和MDMA的药理学特征相似,但作为5-HT2受体亚型,具有稍大的毒性。它在日本是非法的。 (zh)
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  • 806596-15-6
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  • W5G20WN7CL
PubChem
  • 547092
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