The 2006 Dover 400 was the twenty-eighth stock car race of the 2006 NASCAR Nextel Cup Series and the second in the ten-race season-ending Chase for the Nextel Cup. It was held on September 24, 2006 at Dover International Speedway in Dover, Delaware, before a crowd of 145,000. The 400-lap race was won by Jeff Burton of Richard Childress Racing, who started from 19th position. Carl Edwards of Roush Racing finished second and Jeff Gordon of Hendrick Motorsports came in third.