The 2010 AMA Pro Daytona Sportbike Championship was the second running of the AMA Daytona Sportbike Championship, an American motorcycle racing series that acts as a feeder series for the AMA Pro American Superbike Championship. Title sponsors for the series include Sunoco, Amsoil, National Guard, Dunlop, Speedcom and SunTrust. Martín Cárdenas won his first championship riding a Suzuki.