The 2010 Cork Senior Hurling Championship was the 122nd staging of the Cork Senior Hurling Championship since its establishment by the Cork County Board in 1887. The draw for the 2010 opening round fixtures took place on 13 December 2009. The championship began on 1 May 2010 and ended on 10 October 2010. Newtownshandrum were the defending champions, however, they were defeated by Erin's Own in the quarter-finals. On 29 August 2010, Blarney were relegated from the championship following a 1-14 to 1-12 defeat by Blackrock.