The 2015–16 Middle Tennessee Blue Raiders men's basketball team represented Middle Tennessee State University during the 2015–16 NCAA Division I men's basketball season. The Blue Raiders, led by 14th year head coach Kermit Davis, played their home games at the Murphy Center and were members of Conference USA (C-USA). They finished the season 25–10, 13–5 in C-USA play to finish in second place. They defeated Charlotte, Marshall, and Old Dominion to be champions of the C-USA tournament and earn the conference's automatic bid to the NCAA tournament. As a #15 seed, in the first round they upset #2 seed and #2 nationally ranked Michigan State to become the eighth #15 seed to win an NCAA Tournament game. In the second round they lost to Syracuse.