The 2016–17 Duke Blue Devils women's basketball team represented Duke University during the 2016–17 NCAA Division I women's basketball season. Returning as head coach was Joanne P. McCallie entering her 10th season. The team plays its home games at Cameron Indoor Stadium in Durham, North Carolina as members of the Atlantic Coast Conference. They finished the season 28–6, 13–3 in ACC play to finish in a tie for second place. They advanced to the championship game of the ACC women's tournament where they lost to Notre Dame. They received an at-large bid to the NCAA women's tournament where they defeated Hampton in the first round before getting upset by Oregon in the second round.