The 2016–17 FC Anzhi Makhachkala season was the club's second season back in the Russian Premier League, the highest tier of football in Russia, since their relegation at the end of the 2013–14 season. Anzhi finished the season in twelfth, narrowly avoiding a Relegation play-off thanks to their head-to-head record against FC Orenburg, whilst also reaching the Quarterfinals of the Russian Cup, where they were knocked out by FC Ufa.