The 2016–17 Mississippi Valley State Delta Devils basketball team represented Mississippi Valley State University in the 2016–17 NCAA Division I men's basketball season. The Delta Devils, led by third-year head coach Andre Payne, played their home games at the Harrison HPER Complex in Itta Bena, Mississippi as members of the Southwestern Athletic Conference. They finished the season 7–25, 7–11 in SWAC play to finish in seventh place. As the No. 7 seed in the SWAC tournament, they lost to Alcorn State in the quarterfinals.