The 2017–18 Cal Poly Mustangs men's basketball team represented the California Polytechnic State University in the 2017–18 NCAA Division I men's basketball season. The Mustangs were led by ninth-year head coach Joe Callero and played their home games at Mott Athletic Center as members of the Big West Conference. They finished the season 9–22, 4–12 in Big West play to finish in seventh place. They lost in the quarterfinals of the Big West tournament to UC Santa Barbara.