The 2017–18 Southern Illinois Salukis men's basketball team represented Southern Illinois University Carbondale during the 2017–18 NCAA Division I men's basketball season. The Salukis, led by sixth-year head coach Barry Hinson, played their home games at the SIU Arena in Carbondale, Illinois as members of the Missouri Valley Conference. They finished the season 20–13, 11–7 in MVC play to finish in second place. In the MVC tournament, they defeated Missouri State in the quarterfinals before losing to Illinois State in the semifinals. Despite winning 20 games, the Salukis did not participate in a postseason tournament.