The 2018 Mayo Senior Football Championship was the 117th edition of the Mayo GAA's premier gaelic football tournament for senior clubs in County Mayo, Ireland. Sixteen teams competed with the winners going on to represent Mayo in the Connacht Senior Club Football Championship. The championship started with a group stage and progressed to a knock out stage. The winners received the Paddy Moclair Cup. Moy Davitts returned to the top-flight for the first time since their relegation in 2010, having claimed the 2017 Intermediate Championship title with a replay victory over Kiltimagh.