The 2018 Northwestern State Demons football team represented Northwestern State University as a member of the Southland Conference during the 2018 NCAA Division I FCS football season. Led by first-year head coach Brad Laird, the Demons compiled an overall record of 5–6 with a mark of 4–5 in conference play, tying for eighth place in the Southland. Northwestern State played home games at Harry Turpin Stadium in Natchitoches, Louisiana.