The 2019 Houston Cougars football team represented the University of Houston in the 2019 NCAA Division I FBS football season. The Cougars played their home games at TDECU Stadium in Houston, Texas, and competed in the West Division of the American Athletic Conference. They were led by first-year head coach Dana Holgorsen. They finished the season 4–8, 2–6 in AAC play to finish in a tie for fifth-place in the West Division.