The 2020–21 College of Charleston Cougars men's basketball team represented the College of Charleston in the 2020–21 NCAA Division I men's basketball season. The Cougars, led by seventh-year head coach Earl Grant, play their home games at the TD Arena in Charleston, South Carolina as members of the Colonial Athletic Association. In a season limited due to the ongoing COVID-19 pandemic, the Cougars finished the season 9–10, 6–4 CAA play to finish in third place. They lost in the quarterfinals of the CAA tournament to Drexel.