The 2020–21 Oklahoma Sooners women's basketball team represented the University of Oklahoma in the 2020–21 NCAA Division I women's basketball season. The Sooners were led by twenty-fifth year head coach Sherri Coale. The team played its home games at the Lloyd Noble Center in Norman, Oklahoma was a member of the Big 12 Conference. After the season, Sherri Coale retired after twenty five season as head coach of the Sooners. Jennie Baranczyk was announced as the new head coach in April of 2021.