The 2020–21 Xavier Musketeers men's basketball team represented Xavier University during the 2020–21 NCAA Division I men's basketball season as a member of the Big East Conference. Led by third-year head coach Travis Steele, they played their home games at the Cintas Center in Cincinnati, Ohio. They finished the season 13-8, 6-7 in Big East Play to finish in 7th place. They lost in the first round of the Big East tournament to Butler.