The 2021–22 Chicago State Cougars men's basketball team represented Chicago State University in the 2021–22 NCAA Division I men's basketball season. The Cougars were led by first-year head coach Gerald Gillion. They played their home games at the Emil and Patricia Jones Convocation Center as members of the Western Athletic Conference. This was Chicago State's final season in the WAC, and a new conference has yet to be officially announced.