The 2021–22 Marquette Golden Eagles men's basketball team represented Marquette University during the 2021–22 NCAA Division I men's basketball season. The team were led by first-year head coach Shaka Smart and played their home games at Fiserv Forum in Milwaukee, Wisconsin as a member of the Big East Conference. They finished the season 19–13, 11–8 in Big East play to finish a tie for fifth place. As the No. 5 seed, they lost in the quarterfinals of the Big East tournament to Creighton. They received an at-large bid to the NCAA tournament as the No. 9 seed in the East Region, where they lost in the First Round to North Carolina.