The 2021–22 Nepal T20I Tri-Nation Series was a Twenty20 International (T20I) cricket tournament that took place in Nepal from 28 March to 4 April 2022. The participating teams were the hosts Nepal along with Malaysia and Papua New Guinea. The matches were played at the Tribhuvan University International Cricket Ground in Kirtipur. On 12 March 2022, the Cricket Association of Nepal (CAN) confirmed all the fixtures.