Alex de Minaur was the reigning champion from when the tournament was last held in 2019, but chose not to participate this year. John Isner won his sixth Atlanta Open title, defeating Brandon Nakashima in the final, 7–6(10–8), 7–5.
Alex de Minaur was the reigning champion from when the tournament was last held in 2019, but chose not to participate this year. John Isner won his sixth Atlanta Open title, defeating Brandon Nakashima in the final, 7–6(10–8), 7–5. (en)
Alex De Minaur era il detentore del titolo, ma ha scelto di non partecipare in questa edizione. In finale John Isner ha sconfitto Brandon Nakashima con il punteggio di 7–6(8), 7–5. (it)
Mužská dvouhra Truist Atlanta Open 2021 probíhala ve druhé polovině července 2021. Do singlové soutěže atlantského tenisového turnaje hraného na tvrdém povrchu nastoupilo dvacet osm hráčů včetně čtyř kvalifikantů. V sezóně 2020 byl turnaj zrušen kvůli pandemii covidu-19. Obhájcem titulu z roku 2019 byl Australan Alex de Minaur, který do turnaje nezasáhl. (cs)