The 2021 Qualico Mixed Doubles Classic (QMDC21) was held from September 30 to October 3, 2021 at the Banff and Canmore curling clubs in Banff and Canmore, Alberta. The bonspiel was a mixed doubles curling tournament, and was held in a round-robin format with a $30,000 purse. The event was the third edition of the annual Qualico Mixed Doubles Classic. Many of the top Canadian curlers were featured at this event, as it served as one of three direct-entry qualifiers to the 2022 Canadian Mixed Doubles Curling Olympic Trials. The highest qualifying Canadian team that placed in top four qualified for the trials.