The 2021 Guaranteed Rate Skate America was the first event in the 2021–22 ISU Grand Prix of Figure Skating, a senior-level international invitational competition series. It was held at the Orleans Arena in Las Vegas, Nevada on October 22–24. Medals were awarded in the disciplines of men's singles, women's singles, pairs, and ice dance. Skaters earned points toward qualifying for the 2021–22 Grand Prix Final.