The 2021 Washington Mystics season was the franchise's 24th season in the Women's National Basketball Association (WNBA). The regular season tipped off versus the Chicago Sky on May 15, 2021. The Mystics struggled to start the season only winning two of their six games in the month of May. Their fortunes rebounded when they posted a .500 winning percentage through June and in their two games in July before the Olympic break. In closing out their pre-Olympic schedule they won in overtime versus the Chicago Sky to finish the first portion of the schedule with an 8–10 record. Coming back from the break, they faced a tough schedule and posted a 2–6 record, including losing the first four games back from the break. To close out the season, September contained two wins book marked by two losses