The 2021 Women's Twenty20 Cup, known for sponsorship reasons as the 2021 Vitality Women's County T20, was the 12th cricket Women's Twenty20 Cup tournament, taking place in April and May, with 36 teams taking part: 34 county teams plus Scotland and Wales. There was no overall winner, with Hertfordshire, Nottinghamshire, Lancashire, Kent, Gloucestershire and Somerset winning their respective regions.