The 2022 Troy Trojans softball team represented Troy University during the 2022 NCAA Division I softball season. The Trojans played their home games at Troy Softball Complex. The Trojans were led by eighth-year head coach Beth Mullins until she resigned due to health conditions on March 14, 2022. Assistant coaches Taylor Smartt and Holly Ward served as interim Co-Head Coaches for the remainder of the season. They were members of the Sun Belt Conference.