The 2022 United States Mixed Doubles Curling Championship was held from March 8 to 13, 2022 at Bob Suter's Capitol Ice Arena in Middleton, Wisconsin. The championship featured twenty-five teams that played in a triple knockout format, which qualified eight teams for the championship round. From there, four teams advanced to the four team page playoff round. The winning team will represent the United States at the 2022 World Mixed Doubles Curling Championship in Geneva, Switzerland.