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About: 3-Monoacetylmorphine     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:Substance100020090, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substanceDrugyago:WikicatOpioidMetabolitesyago:Matter100020827yago:Metabolite115110796yago:PhysicalEntity100001930drugyago:Substance100020090 New Facet based on Instances of this Class

3-Monoacetylmorphine (3-MAM) or 3-acetylmorphine is a less active metabolite of heroin (diacetylmorphine), the other two being morphine and more active 6-monoacetylmorphine (6-MAM). Because of the acetyl-group in 3-position, 3-MAM has relatively weak affinity to μ-opioid receptors. As 3-O-acetylmorphine-6-O-sulfate (C19H23NO7S), where 6-OH is changed to 6-O-SO3, it can act as a potent, centrally acting morphine derivative and has important analgesic properties.