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About: dbr:Adenomatous_polyposis_coli     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:WikicatProteins, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: ThingBiomoleculegeneBiomoleculeGeneyago:WikicatTumorSuppressorGenesyago:Abstraction100002137yago:Arrangement107938773yago:Chemical114806838yago:Compound114818238yago:Gene105436752yago:Group100031264yago:Macromolecule114944888yago:Material114580897yago:Matter100020827yago:Molecule114682133yago:Ordering108456993yago:OrganicCompound114727670yago:Part113809207yago:PhysicalEntity100001930yago:Protein114728724yago:Relation100031921yago:WikicatGenesyago:WikicatGenesOnChromosome5yago:WikicatHumanGenesyago:WikicatHumanProteinsHumanGeneyago:Sequence108459252yago:Series108457976yago:Substance100019613yago:Suppressor105441468yago:Thing100002452yago:TumorSuppressorGene105441806yago:Unit109465459yago:WikicatProteins New Facet based on Instances of this Class

Adenomatous polyposis coli (APC) also known as deleted in polyposis 2.5 (DP2.5) is a protein that in humans is encoded by the APC gene. The APC protein is a negative regulator that controls beta-catenin concentrations and interacts with E-cadherin, which are involved in cell adhesion. Mutations in the APC gene may result in colorectal cancer.