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About: Aflatoxin B1     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:Toxin115034074, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substanceChemical compoundyago:WikicatMaleReproductiveToxinsyago:WikicatMolecularFormulasyago:WikicatMutagensyago:WikicatMycotoxinsyago:WikicatTeratogensyago:Abstraction100002137yago:Agent109190918yago:CausalAgent100007347yago:Communication100033020yago:Formula106816935yago:Matter100020827yago:Message106598915yago:MolecularFormula106817173yago:Mutagen109364086yago:Mycotoxin115036536yago:PhysicalEntity100001930yago:PlantToxin115036638yago:Poison115032376chemical compoundyago:Statement106722453yago:Substance100020090yago:Teratogen109455998yago:Toxin115034074 New Facet based on Instances of this Class

Aflatoxin B1 is an aflatoxin produced by Aspergillus flavus and A. parasiticus. It is a very potent carcinogen with a TD50 3.2 μg/kg/day in rats. This carcinogenic potency varies across species with some, such as rats and monkeys, seemingly much more susceptible than others. Aflatoxin B1 is a common contaminant in a variety of foods including peanuts, cottonseed meal, corn, and other grains; as well as animal feeds. Aflatoxin B1 is considered the most toxic aflatoxin and it is highly implicated in hepatocellular carcinoma (HCC) in humans. In animals, aflatoxin B1 has also been shown to be mutagenic, teratogenic, and to cause immunosuppression. Several sampling and analytical methods including thin-layer chromatography (TLC), high-performance liquid chromatography (HPLC), mass spectrometry,