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About: Afloqualone     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : umbel-rc:DrugProduct, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substanceDrugyago:WikicatMuscleRelaxantsyago:WikicatSedativesyago:Agent114778436yago:CausalAgent100007347yago:Drug103247620yago:DrugOfAbuse103248958yago:Matter100020827yago:Medicine103740161yago:MuscleRelaxant103800001yago:PhysicalEntity100001930yago:Relaxant104072811drugyago:Sedative104166553yago:Substance100020090umbel-rc:DrugProduct New Facet based on Instances of this Class

Afloqualone (Arofuto) is a quinazolinone family GABAergic drug and is an analogue of methaqualone developed in the 1970s by a team at Tanabe Seiyaku. It has sedative and muscle-relaxant effects resulting from its agonist activity at the β subtype of the GABAa receptor and has had some clinical use, although it causes photosensitization as a side-effect that can cause skin problems such as dermatitis.