About: Alberto Mantovani

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Alberto Mantovani Commendatore OMRI (born 29 October 1948) is an Italian physician and immunologist. He is Scientific Director of Istituto Clinico Humanitas (Humanitas Clinical and Research Center), President and Founder of the Fondazione Humanitas per la Ricerca, and Professor of Pathology at the State University of Milan. He is known for his works in the roles of the immune system in the development of cancer. His research on tumor-associated macrophages (TAM, an acronym he coined) established inflammation as one of the causes of cancer. He was the first to identify monocyte chemotactic protein - 1 / CCL2 in 1983, and PTX3 in 1997. His works revealed the existence of decoy receptors in cell-signalling. He has been the most cited scientist in Italy, and one of the ten most cited immunolog

Attributes	Values
rdf:type	Thing foaf:Person person dul:NaturalPerson Eukaryote Person Human Animal animal eukaryote scientist species schema:Person Scientist
rdfs:label	Alberto Mantovani (en) Alberto Mantovani (de) Alberto Mantovani (medico) (it) アルバート・マントヴァーニ (ja) Alberto Mantovani (pt)
rdfs:comment	Alberto Mantovani (* 29. Oktober 1948 in Mailand) ist ein italienischer Mediziner (Onkologie, Immunologie, Pathologie). (de) Alberto Mantovani (Milano, 29 ottobre 1948) è un patologo, immunologo e divulgatore scientifico italiano. Relativamente al suo livello accademico e di rilevanza nel mondo scientifico, basandosi sull'H-index viene considerato uno dei più influenti scienziati italiani del suo campo. (it) アルバート・マントヴァーニ（Alberto Mantovani、1948年10月29日 - ）はイタリアの医師、免疫学者。ミラノ大学病理学教授を経て、現在はミラノに所在するヒューマニタス大学病理学教授。ミラノ出身。2005年にはイタリア勲章(commendatore)、2016年にはロベルト・コッホ賞を授与された。イタリアで最も被引用回数の多い科学者であり、世界の免疫学者の中でもトップ10に入る。免疫系が腫瘍を攻撃するのではなく、逆にその増殖や転移を助けていることを発見し、それに関わる因子を(tumor-associated macrophages (TAMs))と名付けた。TAMsはまた、腫瘍の血管新生や組織再構築を促し、適応免疫を阻害し、抗癌治療にも影響を与えることが示されている。1983年に炎症性マクロファージを活性化するケモカインとしてMCP1/CCL2を、また、1997年にはケモカインに対する抑制因子であるPTX3/TSG-14を同定し、がん免疫の鍵となりうる一連の経路を明らかにした。さらに、彼の研究によって細胞シグナル上にはdecoy receptorが存在し、炎症性サイトカインの回収役として機能していることが明らかにされた。 (ja) Alberto Mantovani (Milão, 29 de outubro de 1948) é um médico oncologista e imunologista italiano. Recebeu o Prêmio Robert Koch e o de 2016. (pt) Alberto Mantovani Commendatore OMRI (born 29 October 1948) is an Italian physician and immunologist. He is Scientific Director of Istituto Clinico Humanitas (Humanitas Clinical and Research Center), President and Founder of the Fondazione Humanitas per la Ricerca, and Professor of Pathology at the State University of Milan. He is known for his works in the roles of the immune system in the development of cancer. His research on tumor-associated macrophages (TAM, an acronym he coined) established inflammation as one of the causes of cancer. He was the first to identify monocyte chemotactic protein - 1 / CCL2 in 1983, and PTX3 in 1997. His works revealed the existence of decoy receptors in cell-signalling. He has been the most cited scientist in Italy, and one of the ten most cited immunolog (en)
foaf:name	Alberto Mantovani (en)
foaf:homepage	http://www.humanitas-research.org/mantovani-alberto/%7C
name	Alberto Mantovani (en)
foaf:depiction
birth place	Milan
birth place	Milan, Italy (en)
birth date	1948-10-29 (xsd:date)
dcterms:subject	Living people 1948 births University of Milan alumni University of Pavia alumni Physicians from Milan Commanders of the Order of Merit of the Italian Republic Italian immunologists University of Milan faculty
Wikipage page ID	51166707 (xsd:integer)
Wikipage revision ID	1082412933 (xsd:integer)
Link from a Wikipage to another Wikipage	Bethesda, Maryland Humanitas University Pentraxins Cytokine University of Milan University of Pavia Decoy receptors Inflammation Interleukin 1 receptor, type II Lincean Academy Living people Chemokine receptor GAVI Alliance Feltrinelli Prize Tumor-associated macrophage 1948 births Latin honors PTX3 Alberto Mantovani Cell (journal) Mario Negri Institute for Pharmacological Research International Union of Immunological Societies University of Milan alumni University of Pavia alumni Physicians from Milan Chemokine Commanders of the Order of Merit of the Italian Republic Italian immunologists University of Milan faculty dbr:CCL2 Immunology Institute of Cancer Research Interleukin-1 family Milan National Institutes of Health Oncology Order of Merit of the Italian Republic University of Brescia Macrophage University of Insubria Università degli studi di Bari Aldo Moro Robert Koch Prize Decoy receptor
Link from a Wikipage to an external page	http://f1000.com/prime/thefaculty/member/9237130099035118 http://www.humanitas-research.org/mantovani-alberto/%7C http://www.hunimed.eu/tag/alberto-mantovani/ https://air.unimi.it/bitstream/2434/145688/2/Cancer-related%20inflammation_Nature.pdf%7Chdl-access=free http://www.robert-koch-stiftung.de/index.php%3Farticle_id=301&clang=1 https://web.archive.org/web/20160918071212/http:/www.scienceonthenet.eu/documenti/autori/alberto-mantovani
sameAs	Alberto Mantovani Alberto Mantovani Alberto Mantovani Alberto Mantovani Alberto Mantovani Alberto Mantovani Alberto Mantovani Alberto Mantovani

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