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About: Alpha-D-phosphohexomutase superfamily     Goto   Sponge   NotDistinct   Permalink

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The alpha-D-phosphohexomutases are a large superfamily of enzymes, with members in all three domains of life. Enzymes from this superfamily are ubiquitous in organisms from E. Coli to humans, and catalyze a on a substrate. Four well studied subgroups in the superfamily are: 1. * Phosphoglucomutase (PGM) 2. * (PGM/PMM) 3. * Phosphoglucosamine mutase (PNGM) 4. * Phosphoaceytlglucosamine mutase (PAGM) Other enzymes in the superfamily are known to act as glucose 1,6-bisphosphate synthases and phosphopentomutases.