Alphonsine Agahozo (born 18 October 1997 in Nyarugenge, Kigali) is a Rwandan swimmer. She competed in the Women's 50m freestyle event at the 2012 Summer Olympics in London. Agahozo finished in 58th place and did not advance to the semifinals. She competed in the women's 50 metre freestyle event at the 2020 Summer Olympics.