The Amesbury Friends Meetinghouse is a Friends Meeting House at 120 Friend Street in Amesbury, Massachusetts. Built in 1850 under the guidance of John Greenleaf Whittier, it is home to one of the leading Quaker congregations of the region, and historically hosted quarterly meetings for Quakers from across eastern Massachusetts and southeastern New Hampshire. The meetinghouse was listed on the National Register of Historic Places in 2002.