Andromachi "Mary" Mavrogeni Papanikolaou was a Greek laboratory technician and the wife of Georgios Papanikolaou, the Greek pathologist who independently invented the pap test. For 21 years, Mary Papanikolaou volunteered to have her cervix sampled and smeared by her husband to help with his efforts to create the pap test, which has been shown to reduce cervical cancer deaths by up to 80 percent.
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