Anne Kelly Knowles (born 1957) is an American geographer and a specialist in Historical GIS. After teaching for over ten years at Middlebury College in Vermont as a professor of geography, she is now a professor of history at University of Maine. In 2002 she edited the first book ever published with case studies of the use of Historical GIS in various disciplines. She was the guest editor of a special issue of the journal Social Science History about this field.