Antone is a former community in Wheeler County, in the U.S. state of Oregon. Antone is south of U.S. Route 26 between Mitchell and Dayville. A gravel road called Antone Lane runs south of and roughly parallel to Route 26, to which it connects both east of Mitchell, in Wheeler County, and west of Dayville, in Grant County. The road crosses Rock Creek, a tributary of the John Day River, at Antone. The Ochoco Mountains and the Ochoco National Forest are directly south of Antone.