Arlene Blum (born March 1, 1945) is an American mountaineer, writer, and environmental health scientist. She is best known for leading the first successful American ascent of Annapurna (I), a climb that was also an all-woman ascent. She was also a deputy leader of the first all-woman ascent of Denali ("Denali Damsels" expedition), the first American woman to attempt Mount Everest and Executive Director of the Green Science Policy Institut.