About: Ashley Treatment

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The Ashley Treatment refers to a controversial set of medical procedures performed on an American child, "Ashley X". Ashley, born in 1997, who has severe developmental disabilities due to static encephalopathy; she is assumed to be at an infant level mentally, but continues to grow physically. The treatment included growth attenuation via high-dose estrogens, hysterectomy, bilateral breast bud removal, and appendectomy. In June 2016, after 18 years of searching, Ashley's condition was determined to be the result of a de novo (not inherited, i.e. a mutation) and non-mosaic single-nucleotide polymorphism in the GRIN1 gene, which is implicated in neurotransmission.

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rdf:type	Thing foaf:Person person dul:NaturalPerson Eukaryote Person Human Animal animal eukaryote species schema:Person yago:WikicatMedicalControversies yago:WikicatMedicalTreatments yago:WikicatNeurologyProcedures yago:Abstraction100002137 yago:Abstraction105854150 yago:Act100030358 yago:Activity100407535 yago:Care100654885 yago:Cognition100023271 yago:Concept105835747 yago:Content105809192 yago:Controversy107183151 yago:Disagreement107180787 yago:Dispute107181935 yago:Event100029378 yago:Idea105833840 yago:Procedure101023820 yago:PsychologicalFeature100023100 yago:Work100575741 yago:YagoPermanentlyLocatedEntity yago:Right105174653 yago:SpeechAct107160883 yago:Treatment100658082 yago:WikicatDisabilityRights yago:WikicatEndocrineProcedures
rdfs:label	Ashley-Behandlung (de) Ashley Treatment (en) アシュリー・トリートメント (ja) 애슐리 치료 (ko)
rdfs:comment	アシュリー・トリートメント（Ashley Treatment）、あるいはアシュリー療法は、原因不明の脳症による発達障害を持つ1997年生まれ、シアトル在住の児童「アシュリー X（Ashley X）」に実施され、物議を醸した一連の医療処置。本件は2006年10月に掲載された論文『重度の発達障害を持つ子供の成長減衰: 古いジレンマへの新たなアプローチ』（原題: Attenuating Growth in Children With Profound Developmental Disability: A New Approach to an Old Dilemma）にて発表され、2007年1月3日の『ロサンゼルス・タイムズ』に記事が掲載されたことでアシュリー自身の尊厳を巡る論争が激化した。 (ja) 애슐리 치료(Ashley Treatment)는 미국 시애틀의 어린이 "애슐리 X"(완전한 이름을 완전히 밝히지 않기 위해 X를 쓴다.)에게 가해지는, 논란이 있는 일련의 의학적인 치료를 말한다. 애슐리는 1997년에 태어났고, 원인을 모르는 정적인 뇌질환 때문에 발달 장애를 겪고 있다. 이 치료는 호르몬 제제를 통한 성장 방지, 자궁 절제, 양쪽 유방 절제, 맹장 절제를 포함한다. 이 치료는 2차 성징의 진행을 막는 것이 목적이다. (ko) The Ashley Treatment refers to a controversial set of medical procedures performed on an American child, "Ashley X". Ashley, born in 1997, who has severe developmental disabilities due to static encephalopathy; she is assumed to be at an infant level mentally, but continues to grow physically. The treatment included growth attenuation via high-dose estrogens, hysterectomy, bilateral breast bud removal, and appendectomy. In June 2016, after 18 years of searching, Ashley's condition was determined to be the result of a de novo (not inherited, i.e. a mutation) and non-mosaic single-nucleotide polymorphism in the GRIN1 gene, which is implicated in neurotransmission. (en) Die Ashley-Behandlung bezieht sich auf eine Reihe von kontroversen Behandlungen, welche als Erstes an einem Kind aus Seattle, Ashley X(), durchgeführt wurden. Ashley wurde 1997 geboren und ist durch statische Enzephalopathie mit damals ungeklärter Ursache schwer geistig behindert. Die Behandlung beinhaltet das vorzeitige Beenden des Wachstums durch Hormonpräparate, Hysterektomie, beidseitige Mastektomie und Appendektomie. Mittlerweile wurde ein Einzelnukleotid-Polymorphismus im GRIN1-Gen entdeckt. () Der Nachname von „Ashley X“ ist nicht bekannt. (de)
foaf:name	Ashley X (en)
name	Ashley X (en)
foaf:depiction
birth place	Seattle area (en)
dcterms:subject	Neurology procedures Disability rights Medical controversies in the United States Endocrine procedures
Wikipage page ID	10744470 (xsd:integer)
Wikipage revision ID	1103041778 (xsd:integer)
Link from a Wikipage to another Wikipage	Canada Pregnancy Puberty Encephalopathy Mutation Menstruation Breast cancer Developmental disabilities Human rights Peter Singer Decubitus ulcer dbr:Utah_Disability_Law_Center Thelarche George Dvorsky Great Ormond Street Hospital Andrea Bocelli Appendectomy Appendicitis MSNBC Fecal incontinence Hormone therapy Neurotransmission British Medical Association Neurology procedures GRIN1 American Medical Association Not Dead Yet Disability Rights Education and Defense Fund Precocious puberty The Guardian Hysterectomy Disability rights Medical controversies in the United States Archives of Pediatrics & Adolescent Medicine Arthur Caplan Arthur Schafer Endocrine procedures Bioethics High-dose estrogen York Central Hospital Growth attenuation Menstrual cramps New Zealand Seattle Sexual abuse

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