The Astor Place Riot occurred on May 10, 1849, at the now-demolished Astor Opera House in Manhattan and left between 22 and 31 rioters dead, and more than 120 people injured. It was the deadliest to that date of a number of civic disturbances in Manhattan, which generally pitted immigrants and nativists against each other, or together against the wealthy who controlled the city's police and the state militia.