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Asunaprevir (formerly BMS-650032, brand name in Japan and Russia Sunvepra) is an experimental drug candidate for the treatment of hepatitis C. It was undergoing development by Bristol-Myers Squibb and has completed Phase III clinical trials in 2013. Asunaprevir is an inhibitor of the hepatitis C virus enzyme serine protease NS3. Asunaprevir is being tested in combination with pegylated interferon and ribavirin, as well as in interferon-free regimens with other direct-acting antiviral agents including daclatasvir.

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  • Asunaprevir (en)
  • Asunaprévir (fr)
  • アスナプレビル (ja)
  • Асунапревир (ru)
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  • Asunaprevir (formerly BMS-650032, brand name in Japan and Russia Sunvepra) is an experimental drug candidate for the treatment of hepatitis C. It was undergoing development by Bristol-Myers Squibb and has completed Phase III clinical trials in 2013. Asunaprevir is an inhibitor of the hepatitis C virus enzyme serine protease NS3. Asunaprevir is being tested in combination with pegylated interferon and ribavirin, as well as in interferon-free regimens with other direct-acting antiviral agents including daclatasvir. (en)
  • L'asunaprévir (nom de code BMS-650032) est un principe actif en expérimentation pour le traitement de l'hépatite C. Il a été développé par la compagnie pharmaceutique Bristol-Myers Squibb et se trouve actuellement en essai clinique de phase III. (fr)
  • アスナプレビル(Asunaprevir)はC型肝炎経口治療薬の一つである。商品名スンベプラ。日本ではダクラタスビルとの併用療法が臨床試験に付され 、2015年3月に承認された。アスナプレビルはC型肝炎ウイルスの酵素/4Aの阻害剤である。開発コードBMS-650032。なお日本での販売は2021年に中止された。 (ja)
  • Асунапревир (Asunaprevir, ранее BMS-650032, торговое наименование в Японии и России Sunvepra) — ингибитор фермента сериновой протеазы NS3 вируса гепатита C, II волны I поколения. Не имеет регистрации FDA, однако официально зарегистрирован в РФ: здесь применяется в составе безинтерфероновых схем терапии гепатита С генотипа 1 (генотипа 1b в большей степени и 1a в меньшей степени) в комбинации с даклатасвиром и софосбувиром. Производится компанией Bristol Myers Squibb. В Японии для терапии генотипа 1 зарегистрирован комбопрепарат Ximency в составе /даклатасвир/асунапревир. (ru)
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