About: Auger therapy

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Auger therapy is a form of radiation therapy for the treatment of cancer which relies on low-energy electrons (emitted by the Auger effect) to damage cancer cells, rather than the high-energy radiation used in traditional radiation therapy. Similar to other forms of radiation therapy, Auger therapy relies on radiation-induced damage to cancer cells (particularly DNA damage) to arrest cell division, stop tumor growth and metastasis and kill cancerous cells. It differs from other types of radiation therapy in that electrons emitted via the Auger effect (Auger electrons) are released with low kinetic energy. In contrast to traditional α- and β-particle emitters, Auger electron emitters exhibit low cellular toxicity during transit in blood or bone marrow.

Attributes	Values
rdfs:label	Auger therapy (en)
rdfs:comment	Auger therapy is a form of radiation therapy for the treatment of cancer which relies on low-energy electrons (emitted by the Auger effect) to damage cancer cells, rather than the high-energy radiation used in traditional radiation therapy. Similar to other forms of radiation therapy, Auger therapy relies on radiation-induced damage to cancer cells (particularly DNA damage) to arrest cell division, stop tumor growth and metastasis and kill cancerous cells. It differs from other types of radiation therapy in that electrons emitted via the Auger effect (Auger electrons) are released with low kinetic energy. In contrast to traditional α- and β-particle emitters, Auger electron emitters exhibit low cellular toxicity during transit in blood or bone marrow. (en)
name	Auger therapy (en)
foaf:depiction
dcterms:subject	Radiation therapy
Wikipage page ID	37195175 (xsd:integer)
Wikipage revision ID	1095271811 (xsd:integer)
Link from a Wikipage to another Wikipage	Cancer Biasing DNA DNA adduct Platinum Ruthenium Particle accelerator Nuclide Nude mouse Memorial Sloan Kettering Cancer Center X-ray tube Peak kilovoltage Cisplatin Electron Electronvolt Monte Carlo method Cell (biology) Tumor Platinum-based antineoplastic Alpha particle Radiation therapy Nucleic acid double helix Cell culture Cell division Faraday cage Gray (unit) Fluence Ionizing radiation Arsenic Atomic orbital Kinetic energy Synchrotron radiation Auger effect Photon Cis–trans isomerism Metastasis Nanometre Radiation therapy Random walk Scattering
sameAs	Auger therapy Auger therapy Auger therapy
specialty	Radioligand Therapy (en)
dbp:wikiPageUsesTemplate	dbt:Anchor dbt:Citation_needed dbt:Frac dbt:Reflist dbt:SimpleNuclide dbt:Infobox_medical_intervention
thumbnail	wiki-commons:Special:FilePath/Auger_Therapy1.jpg?width=300
synonym	AT (en)
has abstract	Auger therapy is a form of radiation therapy for the treatment of cancer which relies on low-energy electrons (emitted by the Auger effect) to damage cancer cells, rather than the high-energy radiation used in traditional radiation therapy. Similar to other forms of radiation therapy, Auger therapy relies on radiation-induced damage to cancer cells (particularly DNA damage) to arrest cell division, stop tumor growth and metastasis and kill cancerous cells. It differs from other types of radiation therapy in that electrons emitted via the Auger effect (Auger electrons) are released with low kinetic energy. In contrast to traditional α- and β-particle emitters, Auger electron emitters exhibit low cellular toxicity during transit in blood or bone marrow. Due to their low kinetic energy, emitted Auger electrons travel over a very short range: way less than the size of a single cell, on the order of less than a few-hundred nanometers. This very short-range delivery of energy permits highly targeted therapies, since the radiation-emitting nuclide will be in close proximity to the delivery site (e.g. DNA strand) to cause cytotoxicity. However, this is a technical challenge; Auger therapeutics must enter their cell-nuclear targets to be most effective. Auger therapeutics are radiolabelled biomolecules, capable of entering cells of interest and binding to specific sub-cellular components. These typically carry a radioactive atom capable of emitting Auger electrons. The Auger electron emission from the atom is stimulated by radioactive decay, or by external pst (primary system therapy, e.g. x-ray) excitation. (en)
gold:hypernym	Form
prov:wasDerivedFrom	wikipedia-en:Auger_therapy?oldid=1095271811&ns=0
page length (characters) of wiki page	11365 (xsd:nonNegativeInteger)
foaf:isPrimaryTopicOf	wikipedia-en:Auger_therapy
is differentFrom of	Molecular Therapy
is Link from a Wikipage to another Wikipage of	Auger Cisplatin Therapy Auger effect Pierre Victor Auger Radiation therapy List of therapies Auger Therapy
is Wikipage redirect of	Auger Therapy
is Wikipage disambiguates of	Auger
is foaf:primaryTopic of	wikipedia-en:Auger_therapy

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