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About: Bimagrumab     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:WikicatDisordersOfMuscles, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substanceDrugmonoclonal antibodyyago:WikicatMonoclonalAntibodiesyago:Abstraction100002137yago:Antibody115027189yago:Attribute100024264yago:Chemical114806838yago:Compound114818238yago:Condition113920835yago:Disorder114052403yago:Macromolecule114944888yago:Material114580897yago:Matter100020827yago:Molecule114682133yago:MonoclonalAntibody115029781yago:OrganicCompound114727670yago:Part113809207yago:PhysicalCondition114034177yago:PhysicalEntity100001930yago:Protein114728724yago:Relation100031921drugyago:State100024720yago:Substance100019613yago:Thing100002452yago:Unit109465459yago:WikicatDisordersOfMuscles New Facet based on Instances of this Class

Bimagrumab (BYM338) is a human monoclonal antibody developed by Novartis to treat pathological muscle loss and weakness. On August 20, 2013, it was announced that bimagrumab had received a breakthrough therapy designation for sporadic inclusion body myositis (sIBM) by the US Food and Drug Administration. In 2014, Bimagrumab entered Phase II development, with some research indicating clinical effects. Novartis planned to apply in 2016 for FDA approval to treat sIBM patients with bimagrumab.