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About: Bovine leukemia virus     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:WikicatRetroviruses, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: ThingDiseaseyago:Agent109190918yago:AnimalVirus101335659yago:CausalAgent100007347yago:InfectiousAgent109312843yago:LivingThing100004258yago:Microorganism101326291yago:Object100002684yago:Organism100004475yago:PhysicalEntity100001930diseasehistoric placeyago:Retrovirus101336282yago:Virus101328702yago:Whole100003553yago:WikicatRetroviruses New Facet based on Instances of this Class

Bovine leukemia virus (BLV) is a retrovirus which causes enzootic bovine leukosis in cattle. It is closely related to the human T‑lymphotropic virus type 1 (HTLV-I). BLV may integrate into the genomic DNA of B‑lymphocytes as a DNA intermediate (the provirus), or exist as unintegrated circular or linear forms. Besides structural and enzymatic genes required for virion production, BLV contains an oncogene coding for a protein called Tax and expresses microRNAs of unknown function. In cattle, most infected animals are asymptomatic; leukemia is rare (about 5% of infected animals), but lymphoproliferation is more frequent (30%).