Brazil competed at the 2022 World Athletics Championships in Eugene, United States, from 15 to 24 July 2022. The Brazilian Athletics Confederation entered 58 athletes. On 19 July 2022, Alison dos Santos became the first Brazilian man to win a gold medal, with a Championship Record in men's 400 m hurdles. With 1 gold and 1 bronze medals, Brazil finished 19th in the medal table and ranked 13th in the overall placing table with a total of 34 points.