About: Bruce Roth

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Bruce D. Roth (born June 1954) is an American organic and medicinal chemist who trained at Iowa State University and the University of Rochester, and, at the age of 32, discovered atorvastatin, the statin-class drug sold as Lipitor that would become the largest-selling drug in pharmaceutical history (as of 2003). His honours include being named a 2008 Hero of Chemistry by the American Chemical Society, and being chosen as the Perkin Medal awardee, the highest honour given in the U.S. chemical industry, by the Society of Chemical Industry, American section in 2013.

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rdfs:label	بروس روث (ar) Bruce D. Roth (de) Bruce Roth (en)
rdfs:comment	بروس روث (بالإنجليزية: Bruce Roth)‏ هو كيميائي ومخترِع أمريكي، ولد في 1 يونيو 1954. (ar) Bruce D. Roth (born June 1954) is an American organic and medicinal chemist who trained at Iowa State University and the University of Rochester, and, at the age of 32, discovered atorvastatin, the statin-class drug sold as Lipitor that would become the largest-selling drug in pharmaceutical history (as of 2003). His honours include being named a 2008 Hero of Chemistry by the American Chemical Society, and being chosen as the Perkin Medal awardee, the highest honour given in the U.S. chemical industry, by the Society of Chemical Industry, American section in 2013. (en) Bruce D. Roth (* 1952) ist ein US-amerikanischer Chemiker, bekannt für die Entwicklung des Medikaments Atorvastatin zur Cholesterin-Senkung, das unter dem Markennamen Lipitor eines der meistverkauften Medikamente (Stand 2003) wurde. Als Lipitor kam Atorvastatin 1997 auf den Markt. 1996 bis 2007 war er Adjunct Professor an der University of Michigan. 2003 erhielt er den ACS Award for Creative Invention. 2008 wurde er Hero of Chemistry der American Chemical Society, 2013 erhielt er die Perkin Medal und 2015 erhielt er den NAS Award for Chemistry in Service to Society. Er hält über 40 Patente. (de)
dcterms:subject	1954 births Living people Iowa State University alumni University of Michigan faculty 21st-century American chemists
Wikipage page ID	19839383 (xsd:integer)
Wikipage revision ID	1094971253 (xsd:integer)
Link from a Wikipage to another Wikipage	California San Francisco Ann Arbor Perkin Medal Pfizer University of Michigan University of Rochester 1954 births Living people Saint Joseph's University Organic chemistry Tetrahedron Letters Genentech The New York Times Ann Arbor, Michigan Lipitor Statin Iowa State University alumni University of Michigan faculty American Chemical Society Americans Oxford University Press Heroes of Chemistry Atherosclerosis Iowa State University dbr:Atorvastatin 21st-century American chemists Philadelphia Society of Chemical Industry HMG CoA reductase Michigan New York Intellectual Property Law Association Medicinal chemistry Chemical Heritage Foundation Sandoz AG Warner-Lambert dbr:Progress_in_Medicinal_Chemistry
Link from a Wikipage to an external page	http://oasys2.confex.com/acs/225nm/techprogram/P595318.HTM https://books.google.com/books%3Fisbn=0195345762 https://web.archive.org/web/20110614120758/http:/www.scienceblog.com/community/older/2003/C/2003363.html https://web.archive.org/web/20110719094845/http:/chemport.ipe.ac.cn/cgi-bin/chemport/getfiler.cgi%3FID=wNidBpcIilyqFodh0jdbIG8so6dfsexvMYICS9WHsn4BeK66YvCg8oTB4mbqO6mN&VER=E https://www.nytimes.com/2000/02/08/business/pfizer-gets-its-deal-to-buy-warner-lambert-for-90.2-billion.html
sameAs	Bruce Roth Bruce Roth Bruce Roth Bruce Roth Bruce Roth Bruce Roth Bruce Roth Bruce Roth
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has abstract	بروس روث (بالإنجليزية: Bruce Roth)‏ هو كيميائي ومخترِع أمريكي، ولد في 1 يونيو 1954. (ar) Bruce D. Roth (* 1952) ist ein US-amerikanischer Chemiker, bekannt für die Entwicklung des Medikaments Atorvastatin zur Cholesterin-Senkung, das unter dem Markennamen Lipitor eines der meistverkauften Medikamente (Stand 2003) wurde. 1976 erhielt er seinen Bachelor-Abschluss vom St. Joseph´s College in Philadelphia und 1981 wurde er bei an der Iowa State University in organischer Chemie promoviert. Ab 1982 arbeitete er für die Pharmafirma Parke-Davis in Ann Arbor, wo er in den 1980er Jahren Atorvastatin als Hemmer von HMG-CoA-Reduktase fand, die wiederum die Geschwindigkeit der Cholesterin-Synthese im Körper steuert. Atorvastatin wurde von ihm 1985 entdeckt (auf der Suche nach einem Wirkstoff, der eine ähnliche Wirkung wie aus Pilzen bekannten Statinen hatte) und wurde 1986 patentiert. 1986 wurde er Research Associate bei Parke-Davis, 1988 Senior Research Associate, 1990 Abteilungsleiter, 1992 Direktor für Arteriosklerose, Entzündungen und Chemie-Exploration. Danach hatte er Managementpositionen (Vizepräsident für Chemie bei Pfizer Global Research ab 2000) als die Firma von Warner-Lambert und diese von Pfizer übernommen wurden. 2007 ging er zu Genentech als Vizepräsident für Small Molecule Drug Discovery. Als Lipitor kam Atorvastatin 1997 auf den Markt. 1996 bis 2007 war er Adjunct Professor an der University of Michigan. 2003 erhielt er den ACS Award for Creative Invention. 2008 wurde er Hero of Chemistry der American Chemical Society, 2013 erhielt er die Perkin Medal und 2015 erhielt er den NAS Award for Chemistry in Service to Society. Er hält über 40 Patente. (de) Bruce D. Roth (born June 1954) is an American organic and medicinal chemist who trained at Iowa State University and the University of Rochester, and, at the age of 32, discovered atorvastatin, the statin-class drug sold as Lipitor that would become the largest-selling drug in pharmaceutical history (as of 2003). His honours include being named a 2008 Hero of Chemistry by the American Chemical Society, and being chosen as the Perkin Medal awardee, the highest honour given in the U.S. chemical industry, by the Society of Chemical Industry, American section in 2013. (en)
gold:hypernym	Chemist
schema:sameAs	Bruce Roth
prov:wasDerivedFrom	wikipedia-en:Bruce_Roth?oldid=1094971253&ns=0

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