About: Bueno-Orovio–Cherry

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The Bueno-Orovio–Cherry–Fenton model, also simply called Bueno-Orovio model, is a minimal ionic model for human ventricular cells. It belongs to the category of phenomenological models, because of its characteristic of describing the electrophysiological behaviour of cardiac muscle cells without taking into account in a detailed way the underlying physiology and the specific mechanisms occurring inside the cells.

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rdfs:label	Bueno-Orovio–Cherry–Fenton model (en)
rdfs:comment	The Bueno-Orovio–Cherry–Fenton model, also simply called Bueno-Orovio model, is a minimal ionic model for human ventricular cells. It belongs to the category of phenomenological models, because of its characteristic of describing the electrophysiological behaviour of cardiac muscle cells without taking into account in a detailed way the underlying physiology and the specific mechanisms occurring inside the cells. (en)
foaf:depiction
dcterms:subject	Numerical analysis Mathematical modeling Cardiac electrophysiology
Wikipage page ID	61186826 (xsd:integer)
Wikipage revision ID	970045286 (xsd:integer)
Link from a Wikipage to another Wikipage	Electric current Endocardium Monodomain model Temporal discretization Bidomain model Degrees of freedom Cardiac muscle cell Weak formulation Electrical conduction system of the heart Gaussian quadrature Molar concentration Lagrange polynomial Phenomenological model MATLAB Calcium signaling System of equations Action potential Cell (biology) Ion channel Affine transformation Numerical analysis Current density Fixed-point iteration Partial differential equation Cardiac electrophysiology Cardiac muscle Cell membrane Differential equation Isogeometric analysis Tessellation Probability density function Heart arrhythmia Backward differentiation formula Tetrahedron Mathematical modeling Cardiac electrophysiology Tachycardia Hexahedron Hodgkin–Huxley model Tissue (biology) Physiology Integration by parts Newton's method Optimization Toolbox Ordinary differential equation Mathematical model Ventricle (heart) Volt Finite element method Runge–Kutta methods Spiral wave Transmembrane potential Heaviside function
sameAs	Bueno-Orovio–Cherry–Fenton model Bueno-Orovio–Cherry–Fenton model
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thumbnail	wiki-commons:Special:FilePath/BuenoOrovio2.png?width=300
has abstract	The Bueno-Orovio–Cherry–Fenton model, also simply called Bueno-Orovio model, is a minimal ionic model for human ventricular cells. It belongs to the category of phenomenological models, because of its characteristic of describing the electrophysiological behaviour of cardiac muscle cells without taking into account in a detailed way the underlying physiology and the specific mechanisms occurring inside the cells. This mathematical model reproduces both single cell and important tissue-level properties, accounting for physiological action potential development and conduction velocity estimations. It also provides specific parameters choices, derived from parameter-fitting algorithms of the MATLAB Optimization Toolbox, for the modeling of epicardial, endocardial and myd-myocardial tissues. In this way it is possible to match the action potential morphologies, observed from experimental data, in the three different regions of the human ventricles.The Bueno-Orovio–Cherry–Fenton model is also able to describe reentrant and spiral wave dynamics, which occurs for instance during tachycardia or other types of arrhythmias. From the mathematical perspective, it consists of a system of four differential equations. One PDE, similar to the monodomain model, for an adimensional version of the transmembrane potential, and three ODEs that define the evolution of the so called gating variables, i.e. probability density functions whose aim is to model the fraction of open ion channels across a cell membrane. (en)
prov:wasDerivedFrom	wikipedia-en:Bueno-Orovio–Cherry–Fenton_model?oldid=970045286&ns=0
page length (characters) of wiki page	22936 (xsd:nonNegativeInteger)
foaf:isPrimaryTopicOf	wikipedia-en:Bueno-Orovio–Cherry–Fenton_model
is Link from a Wikipage to another Wikipage of	Bueno-Orovio-Cherry-Fenton model Bueno–Orovio–Cherry–Fenton model
is Wikipage redirect of	Bueno-Orovio-Cherry-Fenton model Bueno–Orovio–Cherry–Fenton model
is foaf:primaryTopic of	wikipedia-en:Bueno-Orovio–Cherry–Fenton_model

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